Publications & Papers

Analytical Validation of Protein Biomarkers for Risk of Spontaneous Preterm Birth

June 2017 - Sera's recent analytical study, “Analytical Validation of Protein Biomarkers for Risk of Spontaneous Preterm Birth” has been published in the June issue of Clinical Mass Spectrometry. The study details a rigorous analytical validation of Sera’s liquid chromatography/mass spectrometry (LC/MS) platform for sensitive later-generation Agilent mass spectrometers. MORE >

CLINICAL AND COST IMPACT ANALYSIS OF A NOVEL PROGNOSTIC TEST FOR EARLY DETECTION OF PRETERM BIRTH

December 2016 - Published in the American Journal of Perinatology Reports, the authors of this article concluded that “the use of a prognostic test for reducing spontaneous preterm birth is a dominant strategy that could reduce costs and improve outcomes.” Other findings from the report state that preterm birth risk testing and intervention could result in: MORE >

Preterm Birth: can we do better?

October 2016 - Published in the peer-reviewed journal, Proceedings in Obstetrics and Gynecology, the authors present a clinical treatment protocol for testing women early in pregnancy with a validated biomarker test for preterm birth risk, and administering recommended interventions based on a woman’s individual risk. The paper, Preterm Birth: can we do better? discusses: MORE >

Development and validation of a spontaneous preterm delivery predictor in asymptomatic women

May 2016 - This study, published as an Editor’s Choice article in the May issue of American Journal of Obstetrics & Gynecology, concluded that a serum-based molecular predictor (the PreTRM test) predicts an asymptomatic pregnant woman’s individual risk of spontaneous preterm delivery. This information, early in her pregnancy, may provide clinical utility in identifying women at increased risk at an early stage of pregnancy and allowing for clinical intervention that may help prolong gestational age and improve neonatal outcome. MORE >

Predicting sPTB: What do we do now?

May 2016 - Published in Contemporary OB/GYN, this supplement captured proceedings of a panel discussion hosted by Sera Prognostics at the 2016 Society of Maternal-Fetal Medicine Annual meeting. MORE >

Immunoassay Performance of a Preterm Birth Classifier

March 2016 - Sera Prognostics, Inc. presented data demonstrating correlation between ELISA and MRM-MS at the Society of Reproductive Investigation 2016 Annual Meeting. The results of the data demonstrated a two protein ELISA platform that is highly correlative with LC-MRM-MS results and generates sPTB risk scores with excellent classification performance. MORE >

Development and validation of a spontaneous preterm delivery predictor in asymptomatic women

February 2016 - PAPR investigators presented the findings of the landmark PAPR study at the 2016 Society of Maternal-Fetal Medicine meeting. The conclusions of the study and resulting American Journal of Obstetrics & Gynecology was that a serum-based molecular predictor identifies asymptomatic pregnant women at risk of spontaneous preterm delivery, which may provide utility in identifying women at risk at an early stage of pregnancy to allow for clinical intervention. MORE >

Immunoassay Confirmation of MRM-MS Data Supports a Role for Acute Phase Proteins in the Prediction of Spontaneous Preterm Birth

March 2015 - Sera Prognostics, Inc. presented data demonstrating correlation between ELISA and MRM-MS at the Society of Reproductive Investigation 2015 Annual Meeting. MORE >

Discovery Assay Development of Biomarkers Predictive of Preterm Birth

June 2014 - Sera Prognostics, Inc. presented the development and analytical performance of a highly multiplexed and targeted mass spectrometry-based assay for biomarker discovery and subsequent clinical diagnostic development. MORE >

Proteomic Discovery of Serum Biomarkers Predictive of Preterm Birth

March 2014 - Dr. Jay Boniface presented the strategy and methodology used for the discovery of proteins predictive of preterm birth risk at the 2014 Society for Gynecologic Investigation’s 61st Annual Scientific Meeting. MORE >