Discovery Approach for Preterm Birth Biomarkers Recognized in Publication

MAY 2011 – The innovative proteomic methods used by Drs. M. Sean Esplin and Steven W. Graves to identify novel biomarkers for the prediction of preterm birth were highlighted in the May 2011 issue of the American Journal of Obstetrics and Gynecology.

The quality of the scientific research and its clinical importance were the focus of an accompanying Journal Club Roundtable discussion of this newly published work. Dr. George A. Macones, Chairman of the Department of Obstetrics and Gynecology at Washington University in St. Louis, and Associate Editor of the American Journal of Obstetrics and Gynecology (AJOG), led the discussion on the study, praising the powerful proteomics techniques as an expansive strategy taken by the authors to uncover a broad array of possible predictors.

AJOG Subscribers can link to the full Study Article at: Proteomic identification of serum peptides predicting subsequent spontaneous preterm birth

Esplin MS, Merrell K, Goldenberg R, Lai Y, Iams JD, Mercer B, Spong C, Miodovnik M, Simhan HN, van Dorsten P, Dombrowski M, Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Proteomic identification of serum peptides predicting subsequent spontaneous preterm birth. Am J Obstet Gynecol Vol 204 No. 5 May, 2011 p 391.e1-391.e8

Preterm Birth Study Summary

Journal Club Roundtable Discussion